Sentence examples for malignant evolution from inspiring English sources

Here, the main problem is the late diagnosis of pancreatic cancer, which gives cancer cells enough time for malignant evolution.

Diabetic sclerosing lymphocytic lobulitis of the breast (SLLB) as a complication of long standing diabetes is a benign disease without known tendency to malignant evolution.

These data strongly suggest an active role for an ever-changing microenvironment in the malignant evolution of primary tumors, with macrophages being major players.

Instead, activated wildtype p53 merely holds some of these oncogenic clones in stasis, suppressing their further malignant evolution only as long as p53 remains functional.

While p53 may prevent cancer progression by inducing apoptosis or senescence in some oncogenically activated cells, for other such clones it merely prevents further malignant evolution.

Mortality is related to malignant evolution (local or distant recurrence) and co-morbidity, for neoplasms.

There are different stages of a malignant tumor evolution; described roughly, the main stages are the cellular stage and the macroscopic stage.

The resulting inflammation may contribute to stomach cancer risk both by increasing DNA-damaging agents in the tissue as well as by creating an abnormal tissue environment favoring malignant cancer evolution.

The data accumulated for the last years show that uPA system has a lot of functions in the evolution malignant tumors, including the angiogenesis regulation (including the tumor angiogenesis), cell division, adhesion, and migration of the malignant cells and tumor metastasis [ 2– 4].

An emerging mode of comparison is through new genomic technologies, which, with careful exploitation, may also point to genetic events that are important for malignant human tumor evolution.

For the first time, we report NF1 MZ twins concordant for MPNSTs, with a similar clinical presentation of sciatic nerve PNF, as well as a similar malignant and metastatic evolution.