Sentence examples for malignant development from inspiring English sources

The size of the cyst increased in 30 of the 33 remaining patients, and 12 developed criteria suggesting a malignant development.

Aberrant hypermethylation levels were found even in tumour-adjacent epithelia with no histopathological evidence of malignancy, suggesting that it may represent an early event in oral malignant development.

Wang, C. et al. PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.

The only factor associated with signs suggesting malignant development was an increase in cyst size to more than 5 mm during the follow-up evaluation.

Integrating the mechanisms and functions of MZ and GC B cells and the distinctive features of their pathological counterparts should provide essential clues to the understanding of their malignant development, and should offer new insights into the design of effective treatments for B-cell lymphomas.

Methods: All consecutive patients seen from 1999 to 2005 with highly suspected IPMNs confined to BD without criteria suggesting a malignant development (mural nodule, cyst wall thickness >2 mm, BD diameter >30 mm, or main pancreatic duct involvement) were followed up prospectively using computerized tomography, magnetic resonance cholangiopancreatography, and endoscopic ultrasonography.

Etiological concepts on cancer development, malignant growth, and tumor propagation have undergone a revolutionary development during recent years.

Discordant MZ twin-pairs for replication were selected based on the criteria that one twin was diagnosed at least once with malignant tumour development while the co-twin was never diagnosed with malignant tumour development to date.

Discordant MZ twin-pairs were selected based on the criteria that one twin was diagnosed at least once with malignant tumour development of a solid organ while the co-twin was never diagnosed with malignant tumour development to date, in the period ranging from 4 to 21 years after cancer diagnosis of the co-twin (median = 10.3 years).

PEL-engrafted NOD/SCID (PEL/SCID) mice displayed malignant ascites development with notable abdominal distension, consistent with the clinical manifestations of PEL in humans.

However, we could not detect clear signs of premature malignant disease development due to the perturbed Mcph1 function.