Sentence examples for malignant cycling from inspiring English sources

Different treatment options and protocols are considered for each stage and type of breast cancer, including the use of systemic chemotherapy drugs, cytotoxic for both normal and malignant cycling cells.

These observations suggest that significant sparing of non-cycling malignant cells would result from treatment delivered as a single injection of radiolabelled IUdR.

This suggests no common effect of HUHS1015 on cell cycling among malignant pleural mesothelioma cells.

Glioblastomas contain a heterogeneous mix of cells including rapidly proliferating malignant cells as well as slowly cycling cancer stem/progenitor cells.

Fink [ 12] argued that it is of limited clinical value to differentiate malignant catatonia, excited catatonia, delirious mania, rapid cycling mania, and mania with psychotic features, since ECT is remarkably effective in relieving each of these syndromes [ 23, 24].

The significance of CDK11 as the proposed therapeutic target lies in the possibility of affecting both mitotically cycling and noncycling or quiescent malignant cells because the expression and functions of CDK11 isoforms affect both proliferating and quiescent cells.

Indeed, in this study we demonstrate that expression of CD10 marks malignant ALL cells that are apoptotis-prone and actively cycling and express high levels of the c- myc oncogene.

Based on the above observations, we reasoned that expression of CD10 by malignant B cells from ALL might indicate a special cycling ability as well as a propensity to undergo apoptosis.

This study demonstrates that malignant B cells of CD10-positive ALL are mostly actively cycling, and are apoptosis-prone, whereas the cells of CD10-negative ALL are not actively cycling, and do not undergo apoptosis readily in vitro.

DiI+/SCCs were morphologically distinct and showed a more malignant, invasive and neoplastic phenotype when compared to the fast cycling bulk of cells (DiI−/FCC).

For this purpose we used the MCF10 model of mammary carcinoma in which progressively more malignant mammary epithelial lines were obtained by transformation and subsequent cycling as tumors in nude mice [ 5].