Sentence examples for malignant context from inspiring English sources

[ 10] This finding may indicate that despite their use in a malignant context, the ecdysone constructs behave with similar kinetics to that in normal cells thus implying a general utility in studies of various histological tumor types.

However, the inability to identify populations by marker combinations that correspond to the well-defined stages of pro-B to pre-B maturation raises the question about the relevance of the expression levels of individual surface markers in a malignant context.

Endometrial cancer cell lines, KLE and Hec-1-A and cervical cancer cell line, HeLa, are commonly used as a model to study cancer cell signaling and EMT; we also used human immortalized endometrial stromal cells (Hiesc) to assess whether the observed mechanisms were applicable to normal cells in addition to the malignant context.

To date, very little is known about NME3 function in a non-malignant context.

Very little is known about NME6 function or expression in a non-malignant context.

To our knowledge, the strong ovarian expression of nme3 has never been reported in vertebrates in a non-malignant context.

A similar complex was also purified from non-transformed mouse ESCs, suggesting that this variant PRC1 complex has a biological role in a non-malignant context [ 15].

The action of estrogens is mainly mediated by the classical ER, however, these steroids act also through GPER in both normal and malignant cell contexts, like breast cancer cells and CAFs that are main factors of the tumor microenvironment.

For the remaining seven patients, the treating clinician determined the pleural effusion to be malignant in the context of disseminated malignancy.

In support of this conclusion, a similar epigenetic switch has been described in the context of RA-induced differentiation in the non-malignant setting [ 19].

Context: Malignant melanoma is often lethal, and its incidence in the United States has increased rapidly over the past 2 decades.