Exact(1)
Moreover, noticing that TGFβR1 siRNA only partially rescued the malignant consequence caused by miR-490-3p miR-490-3p miR-490-3p 6), there is reason to believe that adownregulations beyond TGFig signaling pathway should be included in the miR-490-3p regulating network.
Similar(59)
With age, normal prostate epithelial structure often changes, resulting in benign or malignant consequences.
As a consequence, malignant B cells seem to profit from Th cell help similar to healthy B cells.
As a consequence, malignant cells may become insensitive to various anti-cancer drugs.
As a consequence, malignant vascular tumors have been categorized as a single entity, angiosarcoma [ 5], because it was difficult to distinguish whether each angiosarcoma was derived from a blood vessel or a lymph vessel.
Recent work has highlighted increased mevalonate (MVA) synthesis in malignant cells as consequence of increased levels and catalytic efficiency of 3′-hydroxy-3′-methylglutaryl-CoA reductase (HMGCR), the rate-limiting enzyme of cholesterol (CHO) biosynthesis that catalyzes the formation of MVA (Scheme 1).
Recurrence and possible malignant transformation are consequences of incomplete excision.
Anaemia is a common occurrence in patients with cancer, arising either as a result of the underlying malignant disease, as a consequence of myelosuppressive chemotherapy or radiotherapy, or a combination of both (Bokemeyer et al, 2005).
Yet, it still remains uncertain whether aneuploidy is the cause or consequence of malignant transformation [64].
Cancer-specific perturbations of signaling, metabolism, and epigenetics can be a cause and/or consequence of malignant transformation.
These processes are known to be significantly increased in malignant cells as a consequence of the increased cellular proliferation activity [16].
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