Sentence examples for malignant characteristics of from inspiring English sources

Wang, J. et al. Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma.

Mei, D. et al. All-trans retinoic acid suppresses malignant characteristics of CD133-positive thyroid cancer stem cells and induces apoptosis.

Inhibiting αv Integrins Decreases the Malignant Characteristics of Medulloblastoma.

The initiation, growth, and metastasis of tumor not only depend on the malignant characteristics of cancer cells themselves, but also the tumor-promoting microenvironment (Joyce, 2005).

Of more relevance to the current study, emerging evidence has demonstrated that distinct patterns of microRNA expression were found in glioblastomas and indicated that microRNAs play key roles in maintaining malignant characteristics of stem cell behavior, cell proliferation and invasion, and angiogenesis (reviewed in [41]).

Gene Ontology Classification revealed that a variety of genes may represent malignant characteristics of CD24−/low/CD44+ TIC-like cells.

The secreted protein TFF3 has malignant characteristics to promote the invasion of tumor cells by acting both directly on malignant cells and indirectly on the vasculature [ 24].

In addition to the reduction in the glioma size, pathological analysis demonstrated the lack of some important malignant characteristics, typical of the glioblastomas, in the tumors co-injected with apyrase (Table 1).

Aberrant methylation patterns appear to reflect a pre-malignant characteristic of the urinary bladder mainly because UC is a neoplasia with multifocal lesions and elevated recurrence indices [ 73], thus corroborating the hypothesis that epigenetic alterations in cancer may preexist in morphologically normal cells [ 74].

In addition to a role in neural development, early studies also indicated that EN2 had an oncogenic function in breast cancer cells as its forced expression in non-tumorigenic mammary cell lines resulted in a number of malignant characteristics including a loss of cell-to-cell contact and a failure to differentiate in response to lactogenic hormones16.

It also showed highly malignant characteristics evidenced by the presence of many cells suggesting high proliferation with highly positive MIB-1 and p53 expression.