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Although histologic evidence of invasion of basement membrane defines malignant behavior for most epithelial malignancies, the definition of malignant behavior for pancreatic neuroendocrine neoplasms is more complex.
Mechanical deterioration underlies malignant behavior of aneurysmal human ascending aorta.
The mechanical substrate for this malignant behavior is unknown.
RNAi-mediated silencing of ezrin gene reverses malignant behavior of human gastric cancer cell line SGC-7901.
Let's pause here and consider how society tolerates and overlooks malignant behavior.
"I don't think that's an aberration, some sort of malignant behavior," Mr. Shannon said.
Wang, H. et al. The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3.
Our findings indicate that fibroblasts in premalignant microenvironment are involved in premalignant transformation of mammary epithelium and play a role in control the malignant behavior of epithelial cells.
The activation of fibroblasts is driven by decreased miR-200b and miR-200c, which trigger malignant behavior of epithelial cells growth and polarity changes.
The transcription factors ASCL1 and NEUROD1 play crucial roles in promoting malignant behavior and survival of human SCLC cell lines.
In doing so, our work characterizes targetable molecular pathways mediating well-established malignant behavior in diffusely infiltrating astrocytic gliomas, while also revealing discrete examples of how mutational disruption of chromatin regulation impacts the expression of tumor-specific biology.
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