Sentence examples for malignancies have used from inspiring English sources

Most investigations of DAC inhibitors in B-cell malignancies have used class I-specific inhibitors (e.g. romidepsin [11], entinostat [47], and MGCD-0103 [48]). MGCD-0103 [48]

Most studies demonstrating constitutive activation of STATs in solid human malignancies have used either Western blot analysis and/or electrophoretic mobility shift assay (EMSA) as the main methodology.

Previous studies examining NLR thresholds in advanced malignancy have used a cutpoint ranging from 2.5 to 5.0 (Yamanaka et al, 2007; Kao et al, 2010; Chua et al, 2011; Huang et al, 2011).

For these reasons, and the need for strategies to prevent or overcome resistance formation in malignancies, we have used an in vitro and functional cellular assay approach to study the EGFR/AP-1 signal transduction pathway.

In the case of lung cancer, lesion classification has entailed estimation of the probability of malignancy for which purpose some authors have used texture analysis[ 20 22].

Others have used this approach for SN biopsy in different malignancies and for the detection of parathyroid adenoma [17 19].

We have used the model including age, ICD10, and history of malignancy together with categorical values for six physiological measurements.

Hematopoietic malignancies have been reported by other groups using MMTV-cre to drive expression of mutant gene isoforms or to delete tumor suppressor genes (Wagner et al., 2000; Wittschieben et al., 2010; Adams et al., 2011), yet the hematopoietic cell types expressing MMTV-cre have not been fully described.

Furthermore, various risk assessment indices to predict malignancy have been established using clinical and/or imaging parameters.

The fact that chemotherapy using cytotoxic anti-cancer drugs has significant side effects and offers little survival benefit for patients with advanced malignancies has prompted the use of alternative medicine in cancer treatment.

Eμ-TCL1 transgenic mice spontaneously develop CD19+/CD5+/CD23+/− B-lineage lymphoid malignancies, and have been used as a mouse model for chronic lymphocytic leukemia that typically shows CD19+/CD5+/CD23+ immunophenotype.