Sentence examples for malfunctioning spindle from inspiring English sources

One possible mechanism behind nondisjunction is a malfunctioning spindle.

Malfunction of the spindle checkpoint leads to precocious anaphase and chromosomal missegregation, and results in subsequent loss of genetic fidelity.

The micronucleus (MN) assay is an excellent biomarker candidate, since it is able to detect chromosome breakage or malfunction of mitotic spindle caused by aneugenic mechanisms [ 8].

Treatment of paclitaxel arrested HT29 cells with VER-150548 or VX680 resulted in spindle checkpoint malfunction and the exiting of cells from mitosis (Figure 6).

Even if Nlp malfunction in MT nucleation and spindle formation undoubtedly fosters multinucleated progenies, we still need to explore its potential direct contributions to cytokinesis.

Through their ability to induce mitotic checkpoint malfunction, Aurora kinase inhibitors synergize with agents that target the mitotic spindle, such as paclitaxel and nocodazole [21], [22].

Lindsey A. Spindle Washington.

Malfunctioning computers?

"Do not fold, mutilate, or spindle".

A mitotic spindle in a dividing cell.

Spindle cells are not present at birth.