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Mr Sharon, 85, is suffering from a malfunction of several organs including the kidneys, they said.
Genetic loss or malfunction of several proteins essential to PtdIns 3,5) P2 function is deleterious both in yeast and animals (see Jin et al (2008) for references).
Moreover, as indicated by Shi and Weinberg, 28 since the human genome contains genetic redundancy, disruption of a single gene may be selectively neutral, but the malfunction of several genes in a pathway might result in expression of a particular phenotype.
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A lot of those how have unlocked their iPhones have complained of several malfunctions, including unresponsive buttons, sudden screen pause, changing colors of the screen, etc.
This is the result of several malfunctions such as poor interaction and/or communication between the physician and patient, lack of clinical appropriateness and lack of organisational appropriateness.
Three years later, he became the second American to walk in space during a Gemini 9 flight ― something he called the "spacewalk from hell" because of several malfunctions in his spacesuit.
The pool area ventilation system had been malfunctioning for several days, so the heating, ventilation, and air-conditioning system was being regulated manually at the time of the outbreak.
Recent progress in microtechnology has made room for novel applications in neural stimulation as well as for extending our knowledge on several malfunction of the nerval system such as tremor, epilepsy or Parkinson's disease, which belong to the most serious medical issues in the population of developed countries.
The genome of living organisms is constantly exposed to several exogenous and endogenous damaging agents – environmental chemicals, ultraviolet (UV) light, ionizing radiation, reactive oxygen species – that can result in DNA lesions potentially leading to cellular malfunctioning, aging and the onset of several diseases, including cancer and neurodegeneration [ 1, 2].
Regarding the biological meaning: Clustering coefficient demonstrates how tightly connected any miRNA is to its neighbors in the miRNA-miRNA network; thus high clustering coefficient can mean that a gene is typically regulated by several microRNAs which can indicate the robustness of this control – malfunction of one miRNA or even several of them can be overpassed by the remaining miRNAs.
Abnormal viscosity variations in the mitochondrial matrix may induce changes in the mitochondrial network organization and further influence metabolite diffusion, which, consequently, are related to cellular aspects of several diseases and malfunctions, such as cell malignancy, atherosclerosis, diabetes, and Alzheimer's disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com