Sentence examples for malfunction of molecules from inspiring English sources

One of the major defects in cancers is the lack of cells to be driven into the apoptotic mode, due to malfunction of molecules like c- myc (Evan and Littlewood, 1998), ras (White et al, 1995), p53 (Soengas et al, 1999), bcl2 (Haldar et al, 1995), caspases (Schotte et al, 2001) and telomerase (Shay and Bacchetti, 1997).

Generally, a disease is a problem resulting not from malfunction of individual molecules but from failure of the relevant system or network, which can be considered as a set of interactions among molecules.

In addition, the malfunction of multiple reactions/preexisting molecules may result in similar change in the profiles of STAT3N ∗ -STAT3N ∗ and SOCS3.

These observations, together with the fact that the hyh mouse presents a diminished amount of αSNAP in brain, have lead to the conclusion that the alteration in brain development in these animals is principally due to an insufficient amount of protein and not to a malfunction of the mutated molecule [13].

This motivates us to develop a simulation method that can characterize the malfunction of individual reactions or molecules in a biological network so that the exact malfunctioning reactions/molecules can be identified for patients to receive beneficial therapies that consider the interaction of all the components in the disease-related network [ 23].

Introns of lincRNA genes provide an internal control: the absence of correlation for the intronic sequences indicates that the observed connection between evolution and expression has to do with structure and function (or robustness to malfunction) of the mature lincRNA molecules.

The results of detection of malfunctioning preexisting molecules are shown in Tables 7 and 8.

Besides, the influence of malfunctioning molecules not only does reflect the abnormal steady-state values, but also may affect the oscillatory behavior [ 15– 17].

This section shows the results for detecting malfunctioning reactions from the artificial clinical data, while the next section focuses on the detection of malfunctioning preexisting molecules from the data.

We could speculate that clearance of molecules that may potentially contribute to the formation of cell aggregates or be part of malfunctioning cell organelles, is part of a general process of functional restoration after traumatic injury.

Air is made of molecules.