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"The consequences of a zipper malfunction," explains a video about the coat I am wearing today, "can take you out of your zone instantly.
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In this article we present a novel mathematical framework to find enzymes whose malfunction explains the accumulation/depletion of a given metabolite in a disease phenotype.
Assume a metabolite is identified in significantly high concentration and we are concerned with finding enzymes whose malfunction explains its accumulation.
In other words, we are not seeking lethal knockouts but possible malfunctions explaining the observed accumulations/depletions.
However, there is no obvious difference between the bovine and the mouse or human sequences that could explain a malfunction in cattle only.
Therefore, the malfunction of such enzymes may explain a significant increase in the concentration of the metabolite under study.
Establishing a link between SBDS and tRNA modification provides an interesting aspect of crosstalk between cytoskeleton function and translation machinery that may explain a faulty chemotactic phenotype of SBDS malfunction.
But when Knight's new system went live, the firm "experienced a human error and/or a technology malfunction," the firm explained in a regulatory filing on Monday.
It is human interests, not biological malfunctions, that explain the judgments that subordinate members have the relevant biological character.
"I was 21, in college and in a relationship with a boyfriend for two years, I was using birth control and it malfunctioned," Amy explained to Hollywoodlife.com.com
"The aircraft experienced equipment malfunction," a Pentagon spokesman said, in explaining why an F-15E Strike Eagle, an American fighter plane, went down in Libya.
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