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Besides reduced crown size, cleft patients demonstrated simplified crown morphology and malformed teeth [3].
The defect turned up in 46 people from six families; all 46 had TDO symptoms, including kinky hair, malformed teeth, and excessively dense bones.
The most commonly mentioned therapeutic solution in literature is surgical extraction and substitution with Maryland-bridge or prosthetic implants [7, 8] because of the technical difficulty involved in exposition and orthodontic alignment and the uncertain prognosis of such malformed teeth.
The downless (dl) gene mutations in mice have defective hair follicle induction, lack sweat glands, and have malformed teeth.
A compound nectin-1 and nectin-3 mutant mouse shows malformed teeth and dies approximately postnatal day 10 (Yoshida et al. 2010, 2014).
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(1) Unraveling the mechanisms behind the formation of this sophisticated, hierarchical structure is of great interest with respect to understanding the basis of malformed tooth enamel and the development of new bioinspired materials for enamel tissue regeneration and repair.
Previously, we reported that in mice, the p.Tyr64His mutation in the enamel extracellular matrix (EEM) protein amelogenin disrupts the secretory pathway in the enamel-forming ameloblasts, resulting in eruption of malformed tooth enamel that phenocopies human amelogenesis imperfecta (AI).
Her awkward height was compounded by a genetic disorder, incontinentia pigmenti, that scarred her skin and caused her hair to fall out in patches and her teeth to be malformed.
Scanning electron microscopy of molar teeth revealed severely malformed enamel in the K14-Cre p120-cKO mice (Fig. 2B, C, E, F).
Maybe your body is flabbier at 70 than it is at 20, maybe your sex organs are a little more malformed, maybe you've lost some teeth or eyes along the way but you can still party, no matter your age.
Maybe your body is flabbier at 70 than it is at 20, maybe your sex organs are a little more malformed, maybe you've lost some teeth or eyes along the way – but you can still party, no matter your age.
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Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com