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Twenty five eyes of 18 patients (5 females, 13 males) with progressive keratoconus underwent CXL and were enrolled in this prospective study.
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A 53-year-old male with progressive personality change and behavioural problems with cognitive decline.
A 63-year-old male with progressive neurosarcoidosis was treated with infusion of methotrexate.
A 75 -ear-old male presented with progressive gait ataxia and memory loss.
A 48-year-old male presented with progressive abdominal discomfort and weight loss of 3 months duration.
Here we report a 31 years old caucasian male patient with progressive gait disturbance, and severe lower limb proximal weakness since the age of 20 years, associated with subtle facial muscle weakness.
A 55-year old Caucasian male presented with progressive muscle weakness, unintended weight-loss over a period of 6 months, malaise and exercise dependent dyspnea over a period of 4 weeks.
Farrior et al., [ 10] described a male child with progressive vertebral fusion of the cervical, thoracic, and lumbar vertebrae, with additional manifestations, such as absence of one cervical vertebra, clefting of the vertebral bodies, and other few minor non-spinous abnormalities.
In addition, males and females with progressive onset had similar durations of both Phase 1 (median 2.0 years, P = 0.871) and Phase 2 (6.8 versus 6.0 years, P = 0.832).
The third case was a young Asian male who presented with progressive weakness & weight loss for 2 months.
The proband is a 38-year-old Caucasian male, who presented with progressive dyspnea and fatigue of 3 months duration and was found to have pancytopenia.
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CEO of Professional Science Editing for Scientists @ prosciediting.com