Exact(5)
We developed a stochastic two-island model which simulated three genetic scenarios, diploidy, haploidy, and haplodiploidy, with two CI phenotypes being considered for the latter: (1) male development of female progeny; and (2) mortality of fertilized eggs.
Inbreeding increases the probability of homozygosity at the CSD locus (in species with single locus CSD) or at all CSD loci, respectively (in species with multilocus CSD), which results in male development of diploid offspring.
Prior experiments demonstrating a role for corticosteroids in male development of both medaka and flounder are consistent with a male-associated zebrafish allele of preserved 21-hydroxylase activity, and female-associated zebrafish allele of reduced activity.
In haplodiploids, the two CI phenotypes female egg mortality (FM) and male development of female eggs (MD), result in a male biased sex-ratio in the offspring [ 13- 15].
Thus, vinclozolin could act on aromatase, which in turn could act on testosterone, both producing estradiol inappropriately and depriving 5-alpha-reductase of the substrate it needs to produce dihydrotesterone, the androgen necessary for appropriate male development of secondary sex characteristics.
Similar(55)
Compared to males, development of mixed cholesterol GS was significantly common among females (χ test, df = 1, p = 0.029).
Traditional romances and sex farces were supplanted by comedies of arrested male development, defensive glorifications of the right of boys to be boys, occasionally informed by the serious question of what it might mean to be a man.
Thus, it has been proposed that two mechanisms of instability apply to (CTG n CAG n repeats: as in oocytes, expansions occur by DNA repair, while contractions characteristic of male development are the result of DNA replication [ 142].
Dax1 expression was not observed in early S. alburnoides male development at any of the stages analysed (Figure S7).
The ablation of COUP-TFII during pre-pubertal stages of male development results in infertility, hypogonadism and spermatogenetic arrest.
Dmrt1 and wt1 transcripts were found at early stages of male development in S. alburnoides and are most likely implicated in the process of gonad development.
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