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The diagnosis of the malaria was based in the method of the thick blood smear by Walker and examinated directly to the optic microscope, according to norms of the World Health Organization, was carried through in all the individuals [30].
The laboratory diagnosis of malaria was based on microscopic examination of thick blood smears and by nested polymerase chain reaction (PCR) amplification of a species-specific segment of the 18S rRNA gene of human malaria parasites.
"Strictly" defined severe malaria was based on modified WHO criteria [ 19, 22].
Knowledge of complicated malaria was based on caregiver's identification of unconsciousness, convulsion, or fever in a child [ 32].
This definition of malaria was based on the latent period for all Plasmodium species reported in China.
The diagnosis of malaria was based on clinical symptoms, the epidemiological (travel) history and the positive results of microscopic examination of the Giemsa-stained thick and thin blood smears ("gold standard"), the rapid diagnostic tests (RDTs), and PCR assay.
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The best regimen for treating Plasmodium falciparum induced malaria is based on artemisinin and its derivatives which were prescribed as artemisinin combination therapy (ACT).
The economic costs to providers of treating malaria were based on detailed retrospective cost data from health facilities across the study sites between 2006 and 2007.
Severe episodes of malaria were based on the incidence of hospital admission with malaria parasites presented in the pooled analysis for SP sites and site specific publications for non SP IPTi [32].
Deaths attributable to malaria were based on oral reports.
In routine care the treatment of malaria is based on the national malaria treatment guidelines.
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