We hope to discover compounds with potent anti-melanoma efficacy from SLE, just like the discovery of artemisinin from a traditional anti-malaria Chinese medicinal herb Herba Artemisiar Annuae, which was inspired from a record in a TCM classic.
The aim of this study was, therefore, to assess the anti-plasmodial activity and safety threshold of O. quadripartita in Swiss albino mice in an attempt to contribute towards screening traditional medicinal plants for malaria control.
His mentor, August Hofmann, had long been interested in quinine, and its medicinal properties in treating malaria were of great importance at the time.
This ethnobotanical survey was conducted to investigate the pattern of treatment practices and medicinal plants used for malaria therapy in Lagos State, Nigeria.
Recent pharmacological research has highlighted the role of medicinal plants in treating malaria in both countries [ 41, 42], but more research is needed to understand the effects of medicinal plant use during pregnancy.
The current findings were in agreement with studies done on medicinal plants used for malaria such as Dodonaea angustifolia [ 40] and Nigella sativa [ 41].
The chemosuppression showed by chloroquine in the current study was in agreement with other studies on medicinal plants used for malaria such as Artemisia annua [ 34], Annona senegalensis [ 35] and Adhathoda schimperiana [ 36] which showed 90.48, 96.20 and 97.80 %, respectively.
The current finding was in agreement with other reports on medicinal plants used for malaria such as Languas galangal [ 33] and Agelanthus dodeneifolius [ 29] which showed significant 52.00 and 56.00 % chemosuppression, respectively.
The methanol extracts of the five medicinal plants reduced the malaria parasite load in mice during the four-day suppressive test suggesting their suppressive effect on the blood stage of the parasite.
Two antimalarial drugs currently widely used for malaria control originally came from indigenous medicinal plants; quinine is isolated from the Peruvian Cinchona's bark and artemisinins are obtained from the Chinese plant Artemisia annua Linn.
