This gulf in our understanding of immunity to malaria may be addressed by novel application of an established murine model of immune regulation of blood stage infection.
While malaria may be one of the greatest causes of poverty, given the costs it imposes on poor families, it also offers some of the most cost-effective solutions.
Malaria may be on the retreat, but it still kills one African child every minute, so it's unsurprising that Elisabeth Braw's article on the biotech company breeding sterile male mosquitoes for release in malaria-affected areas hit the top spot on GSB's business and development hub this year.
To determine how diagnosis of malaria may be improved by combining the use of rapid diagnostic tests (RDTs) for Plasmodium falciparum malaria with clinical diagnosis by the presence or history of fever compared with clinical diagnosis alone in emergency situations with flood-affected displaced populations in Mozambique.
In the gamble of life, protection against malaria may be preferable, even at the potential cost of suffering from sickle-cell disease.
We observe ping-pong kinetics consistent with one substrate/inhibitor binding site that shows selectivity for the oxidation state of the FAD cofactor, suggesting that selective inhibition of the liver versus red blood cell forms of malaria may be possible.
Breakdown in prevention of malaria may be due to a number of different factors in addition to coverage, including improper use and low adherence by households, changing vector populations and reduced susceptibility of the vector.
But there's new hope that slowing down the transmission of malaria may be possible, thanks to a novel vaccine for mice that causes their blood to kill mosquitoes that bite them.
Uncomplicated malaria may be treated with oral medications.
Prevention of malaria may be more cost-effective than treatment of the disease in the long run, but the initial costs required are out of reach of many of the world's poorest people.
The apparently synergistic effect suggests that infection with both EBV and malaria may be needed to facilitate tumor formation.
