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"The Global Fund should be the social investment bank for the whole malaria eradication strategy, not the social investment bank for very badly affected countries alone," he says.
Therefore, the availability of a vaccine is being regarded as an essential component of a successful malaria eradication strategy [ 4].
Besides the ultimate goal of inducing sterile protection in vaccinated individuals, the prevention of transmission by so-called transmission blocking vaccines (TBVs) is being regarded as an important feature of an efficient malaria eradication strategy.
The story of the "Sardinian Project" (see Technical Appendix, note 1), the greatest antimalaria effort in Europe since the discovery of the cycle of transmission of the disease, needs to be reexamined in the light of the recent debate about the new global malaria eradication strategy (10 ).
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Our model challenges this assumption, in agreement with the measured gametocyte densities [21] and the growing perception that mass administration of antimarial drugs should be an important component of malaria eradication strategies [31] [33].
For future malaria eradication strategies, new, safer radical curative compounds that efficiently kill dormant liver stages (hypnozoites) will be essential.
Mr. Cueto asserts that the politics of the time allowed the medical community to be similarly authoritarian in forcing malaria eradication to be the accepted strategy.
Previous strategies include a successful malaria eradication program (H), ongoing coastal replanting (DC), crop diversification, and increased market-based livelihood strategies (EP).
Skinstage activation of parasite-specific Treg-based systemic immunosuppression provides a fundamentally new, experimentally widely substantiated, immunological rationale, and precise focus, for research and vaccination strategy leading to potentially accelerated malaria eradication.
The use of a dual-color BL assay to monitor different parasite sexual stages provides a proof of principle that this approach can be used on other parasite stages, which has relevant implications for future strategies in the frame of malaria eradication.
Malaria eradication schemes in one area are ineffective unless neighbouring countries adopt similar strategies [ 4].
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Justyna Jupowicz-Kozak
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