Sentence examples for maladaptive role from inspiring English sources

The brain of attack-free CH seems to be characterized, compared to M, by (i) GMV changes, with decrease in a classical pain processing region (frontal cortex) and increase in an atypical region (cerebellum) and (ii) increased FC in key cognitive networks, with a possible maladaptive role.

These data contrast the common hypothesis, that calcineurin mainly has a maladaptive role during the development of myocardial hypertrophy.

They also play a maladaptive role in diseases, including sepsis, atherosclerosis, cancer, and chronic inflammatory disorders, including rheumatoid arthritis and Crohn's disease.

Alterations in cardiac AMPK activity are associated with a number of cardiovascular-related diseases, such as pathological cardiac hypertrophy [ 50], myocardial ischaemia [ 36], glycogen storage cardiomyopathy [ 52] and Wolff Parkinson–White syndrome [ 51], suggesting a possible maladaptive role in such conditions.

In this paper, we present evidence for a biochemical mechanism by which 4‑HNE could trigger increased lipid storage, and discuss possible adaptive and maladaptive roles of the self-reinforcing loop that involves triglycerides and 4‑HNE, in particular, in the context of aging.

Negative appraisals of intrusions are positively correlated with depression symptoms, intrusion-related distress and cognitive avoidance strategies (e.g., Starr & Moulds, 2006; Williams & Moulds, 2008), and have been shown to predict depression symptoms at six month follow-up over and above baseline symptoms, indicating a maladaptive maintaining role (Newby & Moulds, 2011).

Fibrosis plays a central role in maladaptive remodelling processes, especially in the context of cardiovascular diseases.

One psychiatrist observed, "His self-enforced personality traits are highly adaptive to a prisoner role, yet maladaptive to this society".… Thompson and Alyce were divorced in October, 1974, and both of them remarried the following year….

A growing body of evidence suggests a prominent role for maladaptive platelet activation and aggregation during sepsis and ARDS and has begun to underscore the pluripotential influence of platelets on outcomes in critical illness.

In female undergraduates, academic, economic and interpersonal stressors have been found to induce negative mood through the mediating role of maladaptive problem-solving strategies [ 16].

However, to our knowledge, up to now no study has tested the model as a whole, including the role of maladaptive cognitive strategies, focusing on postpartum PTSD.