Sentence examples for making unlikely the from inspiring English sources

BP-mediated TNFα induction was however not suppressed by AhR antagonists, making unlikely the involvement of the typical AhR signalling pathway.

Since the end of the cold war, the E.U. has also played a vital role in tying Central European countries to the West and, in the process, making unlikely the revival of conditions that could reignite a cold war with Russia, or worse.

Anti-CGRP mAbs predictably may cross the BBB at a minimum extent, thus making unlikely the hypothesis that they act at sites of action within the central nervous system.

Our results in confocal analysis of megalin showed that its localization was maintained in the apical surface of caco-2 cells and that it was not retained in the endoplasmic reticulum (figure 4B,C), making unlikely the presence of an interaction with the chimera.

However it has recently become clear that the relatively high incidence of type 1 transitions reported by some earlier PCR-based studies strongly decreases once alternative techniques such as high-throughput pyrosequencing on the 454 platform [19] [22] are employed, thus making unlikely the damage hypothesis.

As shown in Fig. 3D, the percentage of Ki67+ cells among total B cells, as well as CD27− and CD27+ B cells did not differ between patients and controls, making unlikely the possibility that the expansion of distinct CD27− subsets and MZ-like B cells observed in our cKS patients may rely on increased spontaneous turnover.

Although the binding mode of pepstatin A is significantly different from that in other pepsin-like aspartic proteases, its location in the active site makes unlikely the previously proposed hypothesis that HAP is a serine protease.

This is probably due to the short evolutionary distance separating these two clades (Fig. S2), which makes unlikely the fixation by positive selection of mutations specific to one clade with respect to the other.

This finding makes unlikely the possibility that any foreign proteins, including non-eukaryotic proteins, may be present in NB that cannot be explained by simple, physical binding by known proteins to calcium or apatite.

Overall these results make unlikely the involvement of matrix or β1-or β3-integrins in the increased migration of MABs through JAM-A-null endothelial monolayers.

The separation of the beads due to the inhibition of the HGF/MET interaction makes unlikely the emission of light due to the decomposition of singlet oxygen before it can react with the light-emitting beads.