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This is expected to affect the OS observed probably making this endpoint poorly associated to the IPC (see " Results" section).
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Also, the use of hypertension as a dichotomous outcome results in loss of information, which makes this endpoint fairly insensitive to small effects of noise.
The weakness of this endpoint results from the difficulty in distinguishing between tumor-related and treatment-related clinical and imaging changes, and this may make this endpoint quite unreliable, with survival potentially being the only definitive endpoint.
Although Gleason scoring is flawed as an indicator of progression, it still remains one of the best indicators of lymph node involvement, treatment failure and death from PCa (NICE, 2008) and as such is routinely recorded in clinic notes making this a well-documented endpoint to assess.
This could make the endpoint of PFS less reliable.
The sophisticated sensors and the development IC make the endpoint detection a hard task.
It would hire a CitySDK Tourism API hosting provider that would make the endpoint available while providing the bar owner with a simple web page for updating the events information.
Lack of information about metal ion levels and functional results because of patients not participating in all follow-ups, the small number of patients, and multiple endpoints made this an exploratory trial.
Solving cell tower security issues by trying to lock every handset would be like trying to make the internet safe by making Symantec Endpoint Security mandatory for all devices with public IPs.
By making our primary endpoint only 1 month post-release we aim to minimise this form of potentially biased attrition.
Nvidia is making endpoint ML a reality with purpose built chips, but how many of those are on transport trains today?
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