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Of interest is the fact that all proposed dormancy mechanisms focus on the metastatic site (rather than the primary site), making our models particularly relevant [ 37, 49].
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We used the admixture model, which assumes that individuals have mixed ancestry, and did not include sampling origin information in our priors, making our model more stringent.
In the spirit of making our model as simple as possible, but not any simpler, the choice of nodes and interactions was made so as to minimise the complexity without losing essential information.
Following (Bai et al., 2010), we use the margin ranking loss (Herbrich et al., 2000), making our model a margin ranking perceptron (Collins and Duffy, 2002).
Nevertheless, we believe we chose the most typical clinical research situation, making our model relevant to most ethicists and clinical scientists.
It seems likely that the necrotic core of advanced plaques may represent an environment, which is both nutrient poor and hypoxic because of inadequate vascularization, making our model a relevant approach to study the effect of CX3CL1.
And then use that data efficiently to make our models better and better and better.
Although our archive is incomplete, we have decided to make our models and our entire corpus of raw range data available to the scholarly community, with the hope it will spur other researchers to address the problems we have faced.
We then make our models, sometimes recreating the binding exactly and sometimes interpreting them more artistically.
To deploy the resulting models, we extended the Bioclipse decision support framework to support models from LIBLINEAR and made our models of logD and solubility available from within Bioclipse.
Cick here to watch a new episode of Behind the Seams, featuring footage of how we made our models look like they just woke up in a strange place, filled with regret and shame.
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CEO of Professional Science Editing for Scientists @ prosciediting.com