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The holoenzyme of E1 endoglucanase (E1holo) has a cellulose binding domain, which increases its affinity for the cell wall matrix while also making it substantially bigger than the truncated version (126 kDa versus 51 kDa as visualized on a Western blot, not shown).
Abetz said the emphasis of the package was on the regional tourism aspect, making it "substantially different" from the SPC Ardmona situation.
"The preclearance mechanism is making it substantially more difficult for Alabama's current leaders to achieve important, much-needed reforms," the Alabama attorney general wrote in a friend-of-the-court brief.
France subsidises diesel to the tune of 7b euro per year — making it substantially cheaper at the pump.
Ma plans for Perfect Field to churn out photovoltaic solar cells based on amorphous silicon technology, a second-generation technique that requires only a thin film of silicon on a glass substrate, making it substantially cheaper to produce than the prevalent, thicker crystalline silicon technology.
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These cascades have made it substantially more expensive for middle-class families to achieve basic financial goals.
And the employer exemption from taxes on new hires would make it substantially less expensive to hire additional workers.
But Mr. Gore's plan, like Mr. Bush's, would make it substantially more expensive for those who want to stay with traditional Medicare.
A political fishing expedition through a professor's files would make it substantially harder to conduct research and communicate openly with colleagues.
"The VW law makes it substantially less attractive for other E.U. investors to acquire the company's shares with a view to participating effectively in management decisions or controlling the company," the commission said.
Unfortunately, that enlightened ruling was offset when the court, by a closer, 5-to-4 margin, made it substantially harder for plaintiffs who bring successful lawsuits to enforce civil rights and environmental laws to obtain reimbursement for their legal fees.
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