Sentence examples for making it problematic to evaluate from inspiring English sources

However, case-control studies are hampered by several sources of bias involved in analysis of lifestyle risk factors, including differential reporting based on disease status (recall bias) and reverse causation, making it problematic to evaluate genetic markers beyond lifestyle or metabolic risk factors.

As the tax law in Germany for this form of a registered voluntary association (Eingetragener Verein) makes it problematic to pay developers directly, indirect possibilities like Stipends were evaluated.

This makes it problematic to assume that adoption of accounting systems from an institutional field will result in a steady-state of organizational legitimacy.

That makes it problematic to bring in brands.

Due to lack of electricity it makes it problematic to communicate.

However, the constantly changing genome of influenza A viruses makes it problematic to prevent or treat influenza-mediated diseases through targeting the virus itself.

In the case of DMPs, varying healthcare demands between and within patients over time might make it problematic to design a good financial compensation system for DMPs.

This limitation in otherwise informative studies makes it problematic to draw conclusions about the long-term effects of cancer therapy [ 25- 28].

There were barriers prohibiting interviews with advanced MS patients and similarly, communication disabilities, cognitive impairments, depression or fatigue made it problematic to conduct some interviews.

The scarceness of complete genome sequences for eukaryotes makes it problematic to use phylogenetic distribution patterns as evidence for, or against, gene transfer events affecting eukaryotes.

This has made it problematic to identify clearly these contacting segments as part of a universal sequence block alignable across both Bacteria and Archaea [ 3].