Sentence examples for making it inactive from inspiring English sources

Rac1/2 is a small RhoGTPase and can be bound to GDP, making it inactive, or to GTP, making it active.

Several proteases as well as growth factors are known to be capable of cleaving DCN making it inactive against some of the growth factors or collagen it is capable of binding to.

Namely, that it has been suggested to have undergone heavy mutagensis, which was used as a possible explanation why RF2 in K12 strains contain Thr246 (making it inactive upon overexpression), instead of canonical Ala like other E. coli strains (see Dincbas-Renqvist et al., (2000) EMBO J and references therein).

Prior to the reconstitution assay, recombinant GAPDH was incubated first with 0.5 mM H2O2 for 30 min at 37°C to make it inactive (to mimic GAPDH oxidation under cellular environments), and its decreased enzyme activity was confirmed (Appendix Fig S5A).

Protamine binds heparin and makes it inactive.

This protein protein complex might alter the higher order structure of preSATP6 to make it inactive.

When this domain is deleted (as with an N-terminally truncated protein), or if the ubiquitin protease domain is mutated to make it inactive (C14A mutation), the protein with a pathogenic repeat is substantially more toxic in both degree and tissue range of toxicity.

After the hour, make it inactive.

The C189S mutation overcomes the lethal effects of the Q61L mutation by disrupting the isoprenylation site in Cdc42, preventing membrane localization of the protein and making it biologically inactive.

When subjected to cold temperatures it dissociates into dimers and monomers, making it mostly inactive.

It is possible that this N-terminal helix plays a regulatory role by occluding the active site of BLES03 under normal conditions and making it catalytically inactive.