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Consumers' tastes and expectations are changing quickly too, making it hard to build hit products with a long lifespan.
Century-old labor and land laws stifle industry and mobility, making it hard to build factories and create jobs.
In addition, many biotechnology companies specialize in one technology out of many needed to develop drugs, making it hard to build a business without merging.
Lucian Bebchuk, a Harvard law professor and campaigner for corporate-governance reforms, calls this "pernicious": the board would be seeking to stifle legitimate debate among the owners of the company by making it hard to build a majority for change.
This problem hinders scientific progress by making it hard to build on results buried in literature.
The livelihood choices that Maasai face now are shaped by decades of such experiences, perceptions and stories, as well as by complex communal politics, making it hard to build trust and cooperation (West et al. 2006; Adams and Hutton 2007).
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Breaking up the Congo, which has only a tiny outlet to the Atlantic Ocean, would merely create more landlocked countries, making it harder to build a viable economy.
"Now we are in a similar position," one exasperated administration official said Sunday night, "where the headlines will be dominated by the Israeli occupation, making it harder to build steam for the ideas in the president's speech".
In contrast, CDMA networks change base station identifiers much more frequently, making it harder to build an accurate base station database without carrier involvement.
And there is new competition making it harder to build and run a successful VC firm.
Pull-ups can be harder for women because they have a higher limb-to-torso ratio and less testosterone, making it harder to build strength, according to Jordan Metzl, a New York based sports medicine physician.
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