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The Agwu Shale which is not fractured has low transmissivity thus making it difficult to exploit the aquifer.
However, if the apatite is partly carbonated (which is noticeable for instance from a broad ν3 CO3) absorption band in the region 1350 1570 cm−1), then the HPO4 band at 875 cm−1 becomes almost superimposed with the ν2 CO3) band (around 872 cm−1 for B-type carbonate ions), making it difficult to exploit.
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Unfortunately, it is not preserved by composition, which makes it difficult to exploit with component-based design concepts in mind.
Insufficient systematic research data on disease molecular mechanism also makes it difficult to exploit valid therapeutic targets.
This is because smart phones rapidly change their orientation in our hands, which makes it difficult to exploit beamforming with smart phones.
The ecological relationship of these microorganisms with the sponge is still unclear, but it is generally acknowledged that most of them cannot survive in vitro (Uria and Piel, 2009), making it difficult to study and exploit their remarkable biosynthetic capabilities.
In addition, civilian communications and computing technology took the lead away from the military sector, making it difficult to measure the extent to which any country could exploit those technologies by networking computers and sensors for military purposes.
Although the broader manufacturing sector has benefited from automation, several challenges exist within the Australian underground coal industry which makes it difficult to fully exploit these technologies.
The diversity of unconventional oil and gas resources, their location and the technologies required to exploit them, make it difficult to estimate how the cost of recovering unconventional oil and gas differs from traditional wells.
The limitations of the protection measures also make it difficult to identify trafficking victims who are exploited for purposes other than sex, for example children trafficked for the purpose of forced begging.
One of the reasons for ignoring or only partially exploiting temporal correlation is that it often makes it difficult to achieve tractable solutions.
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