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This bacterium exhibits resistance to conventional antibiotics through a variety of virulence factors and there are no effective vaccines, making it difficult to eradicate once it colonizes the respiratory tract [8], [9].
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Once the human immunodeficiency virus (HIV) genome is inserted into the host genome, the virus cannot be removed, which results in latency periods and makes it difficult to eradicate.
"Currently there is a greater complexity of the urban environment that makes it difficult to eradicate the Aedes aegypti mosquito again," said Rafael Freitas, entomologist at the Oswaldo Cruz Institute, Brazil's leading research institute based in Rio de Janeiro.
The ability of Sd1 to gain and retain genes and the possible existence of a carrier state may make it difficult to eradicate.
There are still deep cultural and religious beliefs alongside illiteracy that have made it difficult to completely eradicate the practice.
"It makes it difficult to raise money".
"It obviously makes it difficult to shop".
That makes it difficult to recommend solutions.
It makes it difficult to say anything.
These properties make it difficult to detect.
So it makes it difficult to bow.
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