The scenario of highly heterogeneous phenotypes makes it complicated to identify individual targets for the development of new and specific therapies.
This freeze, the first in a series of "extraordinary measures" undertaken by the Treasury to avoid a federal default, could pose difficulties for local governments nationwide, making it more complicated for strapped localities to manage their already weak finances.
Some of it was quite difficult, like finding a chronology that would embrace various sports without making it too complicated for the reader, but not making it too easy for the reader just to just look at the particular item that might interest them, like just going into the ice-skating section.
Lacking nutrients and energy, a malnourished child is more susceptible to illnesses – making it more complicated for treatment and recovery.
"We have a terrific team, and our managers are terrific managers," Mr. Ells said, "but we have made it too complicated for them and too complicated in a way that they just can't do an excellent job in many cases when it comes to the customer experience". He said any changes would not come at the expense of food safety.
"I wouldn't want too much interactivity — something to do on every page for instance — as I think that would make it too complicated for a young child," Bruna told The Guardian of London last year.
"She doesn't make it too complicated for herself," he said.
All of this makes it very complicated for central banks to work out what is going on in the labour market.
Such remarks have made it increasingly complicated for more pragmatic Iranian politicians to offer alternative ideas when it comes to Syria, with state television stressing daily the line of no compromise on Iran's support for Mr. Assad.
The effects of structure failure due to the significant reduction in wall thickness, which determines the burst strength, make it very complicated for pipeline operators to maintain pipeline serviceability.
