Sentence examples for making indirect comparisons from inspiring English sources

When making indirect comparisons of treatment effect between different trials use of a common comparator, often a placebo, is ideal.

This would not have been possible if we had included BMS as, to date, the direct comparison between biodegradable polymer biolimus-ES and BMS is limited to a single trial, making indirect comparisons through this "weak" common link imprecise and meaningful conclusions difficult.

The study characteristics (table 1) show that normal assumptions for making indirect comparisons between oral topotecan and CAV are fulfilled: all trials included similar patients, the IV topotecan regimens were similar, follow up was similar and a number of the same outcomes are available.

While these studies were conducted by the same investigators and with use of standardized methods, one should be careful making indirect comparisons within the group of third-generation inhibitors.

We considered it unnecessary to make indirect comparisons between regimens, since direct evidence was available for all the comparisons of interest.

We used tests of heterogeneity to make indirect comparisons to investigate whether the treatment effect differed across the different intervention categories.

Due to the lack of standardized assay conditions, large variations in the rate of gene repair are not surprising and make indirect comparisons somewhat dubious.

Existing head-to-head evidence cannot be pooled because of significant differences in trial populations and design, and only one review has attempted to make indirect comparisons using placebo-controlled data (Harry and Zakzanis 2005).

The central purpose of the focus groups was to bring out the differences in what people experienced and to enable them to co-construct and make indirect comparisons between the learning outcomes they experienced from doing either ISS or OSS.

Whilst it would be possible to make indirect comparisons by comparing data from the many separate studies that have investigated QoL in different conditions this would result in a wide range of methodological problems.

The adjusted indirect comparison, first reported by Bucher et al, 6 developed initial methods to make indirect comparisons and has since been extended to the multiple treatment comparison (MTC) meta-analysis, to provide more sophisticated methods for quantitatively addressing indirect comparisons of several competing interventions.