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The inhibitor binds in the ATP binding site making hinge contacts with its amino pyrazole core.
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Here machine learning is used, which uses the number of instances of each of these four types of contact changes for each domain movement to 'learn' from the DBMM to make hinge and shear assignments optimally.
This is where the cohesin loader comes into play, making contacts both at the SMC hinge as well as close to the SMC heads.
Constantly making new contacts.
Amino acid residues identified as making alternate atomic contacts or associated with dynamic hinges appear to be good candidates for mutagenesis and assays, indicating that MD can be strongly predictive for RNAP functional residues.
Patrons stopped making eye contact.
Is it making eye contact?
Making Phone Contact.
Stop making eye contact.
Keep making eye contact.
Making eye contact shows confidence.
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