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Although the same paucity of evidence also prevented us from making firm recommendations, having reviewed the literature and drawn on the combined experience of the working group participants, we are in a position to advise the clinician to consider whether such treatment may be necessary for the patient.
The question raised is whether this present evidence is sufficient for making firm recommendations on HPV screening.
Two of the 74 CPGs with TCM content mentioned that "due to the limited literature involving TCM studies and small sample sizes, more evidence was needed before making firm recommendations" and "further high-quality studies should be conducted to confirm the effects of TCM treatments".
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It is accordingly premature to make firm recommendations here.
However, due to the small numbers of participants and heterogeneity of design of trials to date, it is difficult to make firm recommendations for clinical practice.
These limitations restrict the capacity to make firm recommendations related to the approach and timing of screening and highlight the need for longitudinal validation data.
However, recent international guidelines conclude that existing data are insufficient to make firm recommendations on when and in whom to stop TNFi treatment.
The lack of high quality, empirical evidence making that link limits our ability to make firm recommendations but we suggest the following for consideration: Workforce should be considered as a mediating factor between governance mechanisms and health system outcomes.
A recently updated Cochrane systematic review 'Interventions for vitiligo' showed that the research evidence for treatment of vitiligo is poor, making it difficult to make firm recommendations for clinical practice.
This study was retrospective and lacked a sufficient number of patients with recurrence after the achievement of a pCR to allow us to make firm recommendations for a given treatment option.
It seems too early to make firm recommendations about how best to implement patient decision support into routine practice because approaches that use a 'referral model' consistently report difficulties.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com