Sentence examples for making extrapolations of from inspiring English sources

Second, in making extrapolations of bacteremia rates, we made some assumptions that could have biased our adjusted rates.

The study population was homogenous including only elderly men living within a geographically limited area, so one should be cautious about making extrapolations of these results to other population groups.

However, scaling fluidized beds for dynamic similarity continues to be challenging because flow hydrodynamics at lab-scale are largely influenced by bed geometry making extrapolation of conclusions to large-scales infeasible.

Therefore, in vitro culture conditions for S. aureus and those in vivo are likely much different, making extrapolation of in vitro results with animal infections models less predictable.

First, there was significant heterogeneity in the studies, making extrapolation of conclusions fraught with error.

For this finding, the exact temporal sequencing of events was not ascertained, making extrapolation of exact cause and effect difficult.

In summary, the ORIGIN trials have included a very selected population characterized by high CV morbidity and mortality in spite of mild hyperglycemia making extrapolation of the results to common forms of type 2 diabetes or prediabetes highly questionable.

Commercially available animals may be castrated at birth, which affects hormonally mediated developmental processes, or may be sexually immature at the time of study making extrapolation of data to adult animals problematic.

This variation makes extrapolations of therapeutic concentrations between species difficult.

However, several recent studies have raised reservations over the measurement of ROS production in vitro [ 8– 10], since artificially high levels of metabolic substrates [ 11] and very high partial pressures of oxygen (20% in contrast to approx. 5% in vivo [ 10]) make extrapolations of in vitro results to the in vivo situation potentially problematic [ 7, 8].

An important heterogeneity in the design and the results of these studies was observed, making extrapolations to a clinical impact of copper surfaces difficult.