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Redmond's contribution lay in bioprinting with living cells, and making complex tissues instead of simple sheets.
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Lewis's approach is only one of many in the wider effort to create complex tissues.
A breakthrough in probing how cells create complex tissues and organs.
Gu, Z. ComplexHeatmap: Making Complex Heatmaps.
As with cultured skin, they are finding that their most important allies are the cells that already know how to make these complex tissues.
Transcriptomic studies are important tools for understanding the development and function of the different cell types that make up complex tissues.
Dare to make complex judgments.
Moreover, the fact that tissue-specific stem cells can each only make a limited number of mature cell types makes production of complex tissues from these cells challenging.
They have found that embryonic stem cells grown in this way can spontaneously organise themselves to form the complex tissues that make up eyes, glands and brain tissue.
The researchers also showed that the material could be made into a scaffold to engineer complex tissues.
Here, we review the different cell-based strategies utilized to pre-vascularize engineered tissues and in making more complex vascularized cardiac tissues for regenerative medicine applications.
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