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We again studied the tumours 2 or 3 days following the boost vaccination with Ad.E7, a time point at which there was no significant change in tumour size, making comparisons more equitable.
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For the other coxibs, there was a reasonable, but not overwhelming, number of events for both coxib and NSAID comparators, making comparison more robust.
However, cartilage sampled from visibly intact full thickness regions from both groups make comparisons more valid.
Furthermore, the results indicate great disparities in methodologies used, which make comparisons more difficult.
In general, there are great methodological varieties between studies which make comparisons more difficult.
However, the differences between the TILDA database and these prescription reimbursement databases make comparisons more difficult.
To make comparisons more meaningful between methods we also constrained the DIVA analysis in the same way.
Additionally, in order to make comparisons more meaningful, data for a uniform age category (15 49 years) were used for both males and females to estimate the MNLM.
A similar finding has been reported in stroke subjects, although the diffuse nature of lesions in these subjects combined with the relatively poor spatial resolution makes comparisons more ambiguous [ 52].
In order to make comparison more informative, the figures for YLL are now expressed as a percentage of the total YLL attributable to cancer.
Making comparisons is more difficult than usual and requires a preliminary caution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com