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However, in the MOE preparation, the selected pyrrolidine conformation is different and led to an obvious deviation in the placement of enalaprilat's carboxylate group, thus, making close contacts with the surrounding polar residues infeasible.
Then we insert lysine K85 next to the major groove of DNA at the dyad axis, as it was found to be in 27 out of 30 top-ranked docking positions [28], and oriented the globular domain so that the residues involved in DNA binding (R42, R47, R73, R74, R94, K40, K69, K85, K97, H 25 and H62) are making close contacts with the entry and exit linkers.
acidophila LH2 complex shows the basis for this structural role; nine membrane-spanning carotenoids traverse the membrane, making close contacts with both the nine B800 and eighteen B850 BChls [7].
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In the present case, the ZnO structure-covered superhydrophobic surface is capable of making close contact with water droplets due to large van der Waals' forces, similar to the effect of the gecko's foot hairs.
When the peristome is wet, the fluid films prevent the insects' tarsal adhesive pads from making close contact with the surface, similar to the aquaplaning of a car tire on a wet road.
The benzo[1,3]dioxole moiety is deeply buried, making close contact with Ala397 and Gly232 at the bottom of the cleft.
The two regions in the PBD making close contact with the C-terminal domain, residues 263 268 (loop) and 304 314 (α helix), do not show significant ΔD% between the monomer and dimer.
The side chains of these residues make close contacts with a panel of hydrophobic amino acids, including V84, F87, Y124, V125, and I127 of DAXX (Fig. 2A).
In the D. hansenii Get3 structure, the two nucleotide-binding domains (NBD) face to each other and make close contacts.
Dendrite-like projections of intermediate cells, dispersed between the two cell layers, make close contacts with capillaries through gap junctions.
Ultrastuctural techniques showed morphine immunoreactivity to be concentrated in the cell bodies of basket cells and their endings that make close contacts with Purkinje cell bodies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com