Its goal is to have companies make clinical data about a drug or a medical device available to a wide range of researchers, not just a few handpicked ones.
The Department of Defense, IOM says, should increase its monitoring of possible long-term health effects and make clinical data available to scientists at other institutions.
With regard to the second goal (ii) mentioned above, a potential benefit for patients and prescribers from making clinical trial data accessible will only be achievable if third parties with sufficient technical and methodological capacity would do such secondary data analyses.
Richard Francis, research manager at the UK charity Breakthrough Breast Cancer, said: "We strongly believe that making clinical trial data freely available would decrease the potential for 'spin' by allowing more researchers to investigate the results.
Indeed the overall impact of making clinical trial data accessible should be to decrease the ratio of false-positive to true-positive signals.
All the studies presented in this section will cover data at the patient level and venture to answer clinical level questions including: Prediction of ICU readmission, prediction of patient mortality rate (after ICU discharge and 5 years) and making clinical predictions using data streams.
As a result of these phenomena, oxygen content in the vessels of the microcirculation could be normal, making clinical interpretation of NIRS data complex.
More specifically, to be useful in routine clinical practice, a good predictive model should use clinical data, make prediction at a time suitable for making clinical impact, have high accuracy, and use an appropriate definition of asthma.
Health information technology (HIT) systems have the potential to improve health care quality and outcomes, in part by making important clinical data quickly available.
