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Capsaicin activation of TRPV1 was first investigated by making chimeras between capsaicin sensitive and insensitive orthologs.
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"The whole idea of making chimeras, mixing different animal species or human-animal, has been around for decades," said Lovell-Badge.
Aggregation methods may not be suitable for making chimera rats.
To make Stg chimeras, splenocytes were isolated from WT or TGF-βRII KO Stg mice.
Making comparisons between people.
In all these mutants, residues from the synaptotagmin-7 C2B domain sequence present in the chimera were replaced with the corresponding residues of synaptotagmin-1 to make the chimera more 'synaptotagmin-1 like'.
The two videos were made with Chimera.
Figures were made using Chimera (Pettersen et al., 2004) and the PyMOL Molecular Graphics System (DeLano, 2002).
To address this problem, families of detectors that are chimeras between signal transduction proteins and fluorescent proteins have been designed.
To determine whether this influences tumor type, latency and incidence a comparison was made between conventional mice and chimeras for the three GEMMs (Fig 2E and F and supplementary Fig S2B).
Chimeras between polymerase genes P19 (high expresser) and P15 (low expresser) showed highly distributed effects.
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