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She advanced the frames slowly, projecting the images onto a white board, pointing out techniques and making annotations with dry-erase markers.
Another important advantage of the PDA is that the facility for making annotations is offered.
Identification of relevant articles describing a gene product's function is the essential starting point for making annotations.
In order to allow the waveform to be clearly visible while making annotations, and to allow accurate region selection, the waveform remains at the top of the page (at full width) as the user scrolls down.
One of the reasons for this is because it is very difficult to precisely map gene mentions to organism specific gene identifiers that will be used in making annotations.
In several cases, the workflow submitted to Track II described only a specific slice of a larger curation process, so that the full curation process for some of these databases (MGI, in particular) may be considerably broader than what is captured in Table 4. Generally speaking, MODs report that most papers contain all the information needed for making annotations.
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SVG is supported by graphic editors such as Inkscape, making annotation and application of visual effects to downloaded trees easy.
This required ~40 days of biocurator time, making annotation of all genes (in families with at least one experimentally characterized gene) a feasible ambition for the GO Consortium.
For example, of the 30% of mouse array sequences which were not annotated by Sma3s (SC = 0.7 in Fig. 5), 86% lacked BLAST results, making annotation impossible.
Structures solved by SG projects often bear little resemblance to known proteins in either sequence or structure, making annotation especially challenging.
In humans, mice and dogs, the conserved segments are totally ordered, making annotation of the dog segment easy, thus helping determination of candidate merle genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com