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However, some pathological overlap between genetically distinct disorders has been described, making a genetic diagnosis sometimes difficult.
Importantly: This is not reproductive cloning because you are not making a genetic copy of a person.
In the experimental field of gene therapy, scientists have worked carefully to avoid the momentous step of making a genetic alteration that could be passed along to future generations.
It is also important to note that some of the proteases and substrates in the Notch signaling pathway are also implicated in mutual interactions and lack stringent cleavage sites, making a genetic analysis of these processes difficult.
These problems have been addressed by making a genetic fusion protein of a single chain Fv (sFv) (Begent et al, 1996) antibody with CPG2 (Bhatia et al, 2000).
We conclude that exome sequencing in non-consanguineous couples can provide an effective means of making a genetic diagnosis of lethal autosomal recessive disorders.
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What makes this approach appealing is that omics data can effectively be integrated with cellular level data largely available, making a genetic-cause/phenotypic-effect analysis possible [ 57].
One surprising turn — twins — did not make a genetic problem more likely.
The fact that you cannot make a genetic male sexually attracted to another male by raising him as a girl makes any social theory of sexuality very weak.
It is not that Hispanics are more genetically predisposed to Alzheimer's, say experts, who say the diversity of ethnicities that make up Hispanics or Latinos make a genetic explanation unlikely.
Together, these observations make a genetic cause of the cryptorchid problem on the AP unlikely.
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