Interestingly, the orange cluster is not enriched for any cell type, and we would conclude that transcripts in the orange cluster represent differential gene expression due to transcriptional differences between the samples (as opposed to difference in the cellular makeup of the samples) and are suitable for further analysis using traditional approaches.
But only five of the nine pollsters who fielded surveys in South Carolina in January reported the racial makeup of their samples.
According to the executive summary as described in The Los Angeles Times article, the audit criticized the makeup of the sample audience Nielsen recruited in New York to use the people meters.
The results are robust to alternative estimation techniques, measures employed to operationalize key concepts, and the industrial makeup of the sample.
Given that the ages mentioned are relatively young and similar, the makeup of the sample group and how finely the ages are separated may significantly affect the determination of risk factors associated with age [29].
Just like poll numbers can be altered by the makeup of the sample, Election Day results -- "the only poll that matters" -- can be altered by the makeup of the actual electorate.
This high-throughput technology simultaneously measures expression levels in thousands of transcripts, providing a snapshot of the molecular makeup of a sample.
Racial makeup of the sample was: 69% Caucasian, 13% Asian, 8% Hispanic/Latino, 5% Black, and, 5% other or mixed race.
In addition, the small size and makeup of the sample (e.g., participants were primarily caregivers from Canada) could limit generalizability to the population of haemophilia A patients and caregivers.
At present, multiple factors have improved the ability to measure allelic ratios at single SNPs in differentially processed areas of a transcript, including increasing read depth and incorporating the genomic makeup of the sample into statistical analyses [ 14, 26, 27, 32, 33].
