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In Uganda, the disease is pandemic, and its devastating effects, makes this virus a major concern for food security in central and east Africa [ 4].
Although the incidence of human infection with B virus is low, a death rate of >70% before the availability of antiviral therapy makes this virus a serious zoonotic threat.
More than one-half million persons have been infected with OROV, which makes this virus a public health threat in tropical and subtropical areas of Central and South America (5 ).
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"Nobody was going to make this virus in his garage.
Because bioterrorists can't make this virus, it's too complex, you need a lot of expertise.
These characteristics make this virus difficult to control.
Its low sequence similarity to other hantaviruses should make this virus serologically distinct from other hantaviruses, as shown for TPMV (10 ).
In contrast to FCV, MNV is transmitted by the fecal-oral route, thus making this virus a promising surrogate for human NoVs.
The expansion of the geographic distribution of HPAIV (H5N1) in wild birds and poultry and the virus's repeated interspecies transmission to humans make this virus a substantial pandemic threat.
The specific probe hybridization pattern obtained from each virus makes this approach a powerful tool for high throughput plant certification purposes and also for virus discovery if the new viral genomic sequences have partial similarity with the microarray probes.
With the development of high capacity mammalian cell bioreactors, the relative ease of propagation of the virus in cell culture without the need for rigorous purification and inactivation of the virus makes this an attractive alternative to production of inactivated vaccines in eggs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com