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The mechanism of action of the bone morphogenetic protein (BMP) family theoretically makes these molecules candidates for rapidly enhancing local bone structure.
A combination of high antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA), without hemolytic activity and proteolytic stability makes these molecules promising candidates for novel antimicrobial therapeutics.
Structural stabilization of them followed by intramolecular as well as intermolecular H-bonds makes these molecules as perfect examples in molecular recognition with self-complementary donor and acceptor units within a single molecule.
Structural stabilization followed by intramolecular as well as intermolecular H-bonds makes these molecules as perfect examples in molecular recognition with self-complementary donor and acceptor units within a single molecule.
Combination of chirality with electroactivity makes these molecules unique in the current oligothiophenes literature.
Moreover, the tightly regulated cell type specificity of miR expression makes these molecules amenable to modulating function of individual cell types.
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"The basic idea was, 'How do we make these molecules smaller' " without diminishing their effects?
A great challenge facing the pharmaceutical scientist is making these molecules into orally administered medications with sufficient bioavailability.
Little is known about their roles, but their high stability and easy quantification make these molecules potential biomarkers.
Furthermore, intensive investigations of the pharmaceutical and toxicological properties of HDACis as anti-cancer drugs make these molecules the most advanced anti-latency agents in clinical trials.
Surprisingly, these compounds exhibited excellent selectively index values ranging from 900 to 1800 making these molecules promising candidates as antiparasitic agents.
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Justyna Jupowicz-Kozak
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