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By focusing on mechanical forces that affect cell behavior, scientists in a sense try to get to the root of what makes these cells tick.
The ability of mesenchymal stem cells (MSCs) to differentiate into other cell types makes these cells an attractive therapeutic tool for cell transplantation.
Accordingly, the multipotential capacity of MSCs, their accessible origin, and high ex vivo expansive potential, makes these cells attractive as tools for tissue engineering and cell-based therapy.
Finally, we show that cartilage constructs generated from CD90pos PαS cells are remodeled into bone organoids encompassing functional endothelial and hematopoietic compartments, which makes these cells suited for bone tissue engineering.
This feature of NK cell biology makes these cells an effective and valid tool for rapidly eliminating virus-infected cells or tumor cells, serving as the body's first line of defense.
This difference is causally related to a differential response to transforming growth factor beta, since overexpression of protein kinase C theta, but not of protein kinase C alpha or zeta, in embryonic myoblasts makes these cells sensitive to transforming growth factor beta.
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rad3Δ cells are also extremely sensitive to MMS and constitutive expression of G1/S transcripts makes these cell moderately more resistant (Figure 3B).
And now we've shown we can reverse this behavior and make these cells behave as they should.
"Now we've shown we can reverse this behavior and make these cells behave as they should," Weyand told me.
Warming up to operational temperatures may take several hours, making these cells unsuitable for vehicles.
The closer clustering of EBV transformed normal lymphoblasts to cancer cell lines suggest the transformation process has made these cells more cancer-like.
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