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The possibility that the biogenesis of exonic miRNAs destabilizes the corresponding protein-coding transcript and reduces protein synthesis makes their characterization very intriguing and suggests a new mechanism of post-transcriptional regulation of gene expression.
Moreover, the possibility that the biogenesis of exonic miRNAs could destabilize the corresponding protein-coding transcript and reduce protein synthesis makes their characterization very intriguing and suggests a possible novel mechanism of post-transcriptional regulation of gene expression.
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These peptides result from the complex processing of prohormone proteins, making their characterization both challenging and resource demanding.
Histone post-translational modifications (PTMs) have been linked to a variety of biological processes and disease states, thus making their characterization a critical field of study.
Transposon insertion polymorphisms can translate into phenotypic differences in plants and animals and are linked to different diseases including human cancer, making their characterization highly relevant to the study of genome evolution and genetic diseases.
As mentioned above, although it has long been recognized that lymphocytes invade acutely injured muscle, very little is known about their role in these conditions, mainly due to the very small number of these cells within the muscle, making their characterization difficult.
To further confound the problem, they can be very far away from the target genes or even can be located on a different chromosome [ 15], making their characterization extremely difficult by computational methods such as comparative genomics approaches, although there are successful examples, in particular for developmental enhancers that tend to be more conserved [ 16, 17].
This is an important breakthrough, as the length of the synthesized SWNTs, and their high alignment, makes their electrical characterization and device fabrication much more accessible than ever before.
However, the evolutionary diversification of protein families often leads to structural differences, which makes their phylogenetic characterization difficult.
But Claverie, a geneticist at Le Centre National de la Recherche Scientifique (CNRS) Structural and Genomic Information Laboratory in Marseille, France, believes that the Mimivirus's complexity should make researchers rethink their characterization of viruses as nonliving.
This makes the characterization more complex.
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