Sentence examples for makes quite difficult from inspiring English sources

Overlapping of this fast deactivation with catalytic reaction makes quite difficult the reliable determination of kinetic parameters.

Furthermore, the 19 true fusions were part of a set of more than 130000 events, which makes quite difficult the task of purging the false positives.

"We are not far from a tipping point where they are having to make quite difficult decisions," he said.

In the figure supplement there are some clearer examples, but the yellow highlighting in 2a makes it quite difficult to make out the pauses.

"Sometimes, if you have a poor result, you have to wait a period of time to fix it, which makes it quite difficult.

Over the last decennia welfare and most of all, food intake habits have changed anthropometry, which makes it quite difficult to compare these results with data that were obtained 20 years earlier.

However, if you are tying them to a chair, each wrist can be tied and secured separately with one wrist tied to one arm of the chair and the other wrist to the other arm of the chair as well, as this makes it quite difficult for them to try and get free.

"This makes it quite difficult to plan ahead".

This all makes it quite difficult to measure their temperature.

I suspect I am not alone among his acquaintances in this respect, and he sometimes makes it quite difficult for others to like him.

Another broadcasting veteran said: "He actually makes it quite difficult to agree with him: it doesn't matter how far you go towards him, he will always move himself so that he's at a more extreme position".