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Aβ dimers are found in equilibrium between various topologies, and the absence of common structural features shared by the four species makes problematic the design of a unique inhibitor for blocking dimers.
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Think of the Internet: an unimaginably powerful tool for education but also a Wild West of random self-expression in which anyone can say anything about anything (or anyone) and have it "published," and which has already made problematic the line between truth and falsehood, expert and amateur opinion, authentic and inauthentic identities, reality and fantasy.
Although the remark has often been read as a pioneering expression of monotheism, this reading is made problematic by the nearby reference to 'gods' in the plural in the first line and the possibility that Xenophanes sought to highlight not the one god but rather the one greatest god (cf. Homer, Iliad 12, 243 for the use of 'one' (Greek heis) reinforcing a superlative).
Interpreting such data is also made problematic by the need for adjustment of confounding factors that may modify the relationships between process and outcome, which may further compound inaccuracies created through their collection in routine clinical practice [ 49- 51].
So even shows made problematic by the recent tragedy appeared as originally intended.
Ms. Mitchell persisted, noting that in previous cases where people associated with both campaigns had made problematic remarks, the campaigns had taken aggressive action.
Their value, however, is made problematic by the fact that all such documents were written by foreigners, mainly Germans who, in the course of their centuries-long eastward expansion, subjugated the Baltic peoples and exterminated some of them.
Desperate for preferment, he made connections where he could (including important friendships with the Countess of Bedford and Magdalen Herbert), he produced defences of the king like a "masterful groveller", and he even considered offers of entering the priesthood - something his secular interests, and his widely known early reputation as a man-about-town, made problematic, to say the least.
(A situationship is an unofficial relationship with no title and no boundaries, which will make things problematic!) The topic of dating got brought up again one day, and come to find out, he has been seeing someone else this whole time, but tries to downplay by saying "I still have feelings for you; I just want to take it slow".
Thus Bohr makes the problematic suggestion that the very expression "Niels' system" refers to conditions for predicting the future behavior of Niels' system.
He's making the (problematic) observation that the other kid speaks with what he thinks is a "white accent" (intonation, inflection, hard consonants, types of slang, fully pronouncing words with -ing, etc).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com