Sentence examples for makes it rather challenging from inspiring English sources

Second, neutrophils are known to quickly migrate from the periphery to their destination points, which makes it rather challenging to reliably measure their stimulated proliferation by analyzing peripheral blood samples.

Which, ergo, makes it rather appealing.

That makes it more challenging.

This makes it more challenging.

But the current economy makes it challenging.

So that makes it challenging too.

However, the lack of dedicated chaperones (i.e. SHQ1 and NAF1) and accessory factors for the assembly of a DKC1 complex in E. coli made this task rather challenging, resulting in low yields after purification.

At the same time, a growing number of airlines have changed their program earnings structures to reward travelers based on price paid rather than distance flown, making it increasingly challenging to easily collect enough points for an award seat.

Make it more challenging.

Despite these successes, the high-charge density of LRHs makes a complete exfoliation rather challenging.

The major weaknesses of the TV model are blocking and staircasing effects, false-edge generation near edges, and non-differentiability property at zero a situation that makes the numerical implementation rather challenging.