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Being small makes it hard to develop new bikes or to buy good components at a decent price.
(Such constant change makes it hard to develop antiviral drugs that will remain effective for long, and it has also presented a significant obstacle to the development of an AIDS vaccine).
If you're being told what to do, you fall into a position of helplessness or disempowerment, which makes it hard to develop this head of steam, this effortful strength and self-control and willpower.
"The lack of large institutions like banks makes it hard to develop a center of gravity for the city," said Mr. Koltai, who was an executive vice president at Warner Brothers before starting Event.411 in 1996.
In fact, the lack of features like dataset caching, accumulators and broadcast variables, and native workflows support, makes it hard to develop scientific applications.
Critics of prohibition have long argued that banning an intoxicant encourages bad habits and makes it hard to develop a culture of responsible use.
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"The alternative is to have one drug that simultaneously hits several, often related bacterial targets making resistance harder to develop," Lee says.
This makes it harder to develop elite institutions.
And — Catch-22 — a result is fewer ordinary cyclists on the road, which makes it harder to develop a safe bicycling network.
Some do get monthly security updates, but others get Android version updates sometimes years after Google releases new versions, creating so-called fragmentation that makes it harder to develop apps and services.
It also makes it harder to develop effective vaccines, and although you can engineer a new jab for each strain, governments often fail to persuade enough people to take it up.
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